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aperio at2 digital whole slide scanning  (Danaher Inc)


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    Danaher Inc aperio at2 digital whole slide scanning
    A) Msi2 is expressed in the Lin - EpCAM + lung epithelial cells of Msi2 GFP/+ (M2GFP) reporter mice. Representative FACS plots shown for non-reporter (Msi2 +/+ , left) and M2GFP reporter mouse lungs (Msi2 eGFP/+ middle). Frequency of M2GFP-expressing cells in lung epithelia (right; n = 2 non-reporter, n = 5 reporter). Data represented as mean ± SD, one outlier identified and removed using the Grubb’s test, ***p < 0.001 by Student’s t-test. B-C) Msi2 is expressed in the known stem cell populations of the distal lung. B) Frequency of Msi2 expression in the Lin - EpCAM + Sca1 + enriched Club/BASC and the Lin - EpCAM + Sca1 - enriched <t>AT2</t> cell populations (n=5). C) Representative images of cytospins from M2GFP reporter mouse Lin - EpCAM + lung epithelial cells showing expression of Msi2 expression in Club cells (top row, marked by CC10 staining) and AT2 cells (bottom row, marked by SPC staining). D) Representative images of Msi2 in tumors from KP f/f mice; some tumors display ubiquitous expression of Msi2 (left), while others display more heterogeneous expression (right).
    Aperio At2 Digital Whole Slide Scanning, supplied by Danaher Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/aperio+at2+digital+whole+slide+scanning/bio_rxiv__2024__04__11__589053-143-5-11
    Average 86 stars, based on 1 article reviews
    aperio at2 digital whole slide scanning - by Bioz Stars, 2026-11
    86/100 stars

    Images

    1) Product Images from "Regulation of lung cancer initiation and progression by the stem cell determinant Musashi"

    Article Title: Regulation of lung cancer initiation and progression by the stem cell determinant Musashi

    Journal: bioRxiv

    doi: 10.1101/2024.04.11.589053

    A) Msi2 is expressed in the Lin - EpCAM + lung epithelial cells of Msi2 GFP/+ (M2GFP) reporter mice. Representative FACS plots shown for non-reporter (Msi2 +/+ , left) and M2GFP reporter mouse lungs (Msi2 eGFP/+ middle). Frequency of M2GFP-expressing cells in lung epithelia (right; n = 2 non-reporter, n = 5 reporter). Data represented as mean ± SD, one outlier identified and removed using the Grubb’s test, ***p < 0.001 by Student’s t-test. B-C) Msi2 is expressed in the known stem cell populations of the distal lung. B) Frequency of Msi2 expression in the Lin - EpCAM + Sca1 + enriched Club/BASC and the Lin - EpCAM + Sca1 - enriched AT2 cell populations (n=5). C) Representative images of cytospins from M2GFP reporter mouse Lin - EpCAM + lung epithelial cells showing expression of Msi2 expression in Club cells (top row, marked by CC10 staining) and AT2 cells (bottom row, marked by SPC staining). D) Representative images of Msi2 in tumors from KP f/f mice; some tumors display ubiquitous expression of Msi2 (left), while others display more heterogeneous expression (right).
    Figure Legend Snippet: A) Msi2 is expressed in the Lin - EpCAM + lung epithelial cells of Msi2 GFP/+ (M2GFP) reporter mice. Representative FACS plots shown for non-reporter (Msi2 +/+ , left) and M2GFP reporter mouse lungs (Msi2 eGFP/+ middle). Frequency of M2GFP-expressing cells in lung epithelia (right; n = 2 non-reporter, n = 5 reporter). Data represented as mean ± SD, one outlier identified and removed using the Grubb’s test, ***p < 0.001 by Student’s t-test. B-C) Msi2 is expressed in the known stem cell populations of the distal lung. B) Frequency of Msi2 expression in the Lin - EpCAM + Sca1 + enriched Club/BASC and the Lin - EpCAM + Sca1 - enriched AT2 cell populations (n=5). C) Representative images of cytospins from M2GFP reporter mouse Lin - EpCAM + lung epithelial cells showing expression of Msi2 expression in Club cells (top row, marked by CC10 staining) and AT2 cells (bottom row, marked by SPC staining). D) Representative images of Msi2 in tumors from KP f/f mice; some tumors display ubiquitous expression of Msi2 (left), while others display more heterogeneous expression (right).

    Techniques Used: Expressing, Staining



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    A) Msi2 is expressed in the Lin - EpCAM + lung epithelial cells of Msi2 GFP/+ (M2GFP) reporter mice. Representative FACS plots shown for non-reporter (Msi2 +/+ , left) and M2GFP reporter mouse lungs (Msi2 eGFP/+ middle). Frequency of M2GFP-expressing cells in lung epithelia (right; n = 2 non-reporter, n = 5 reporter). Data represented as mean ± SD, one outlier identified and removed using the Grubb’s test, ***p < 0.001 by Student’s t-test. B-C) Msi2 is expressed in the known stem cell populations of the distal lung. B) Frequency of Msi2 expression in the Lin - EpCAM + Sca1 + enriched Club/BASC and the Lin - EpCAM + Sca1 - enriched <t>AT2</t> cell populations (n=5). C) Representative images of cytospins from M2GFP reporter mouse Lin - EpCAM + lung epithelial cells showing expression of Msi2 expression in Club cells (top row, marked by CC10 staining) and AT2 cells (bottom row, marked by SPC staining). D) Representative images of Msi2 in tumors from KP f/f mice; some tumors display ubiquitous expression of Msi2 (left), while others display more heterogeneous expression (right).
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    digital whole slide scanning system aperio at2  (HistoWiz Inc)
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    A) Msi2 is expressed in the Lin - EpCAM + lung epithelial cells of Msi2 GFP/+ (M2GFP) reporter mice. Representative FACS plots shown for non-reporter (Msi2 +/+ , left) and M2GFP reporter mouse lungs (Msi2 eGFP/+ middle). Frequency of M2GFP-expressing cells in lung epithelia (right; n = 2 non-reporter, n = 5 reporter). Data represented as mean ± SD, one outlier identified and removed using the Grubb’s test, ***p < 0.001 by Student’s t-test. B-C) Msi2 is expressed in the known stem cell populations of the distal lung. B) Frequency of Msi2 expression in the Lin - EpCAM + Sca1 + enriched Club/BASC and the Lin - EpCAM + Sca1 - enriched <t>AT2</t> cell populations (n=5). C) Representative images of cytospins from M2GFP reporter mouse Lin - EpCAM + lung epithelial cells showing expression of Msi2 expression in Club cells (top row, marked by CC10 staining) and AT2 cells (bottom row, marked by SPC staining). D) Representative images of Msi2 in tumors from KP f/f mice; some tumors display ubiquitous expression of Msi2 (left), while others display more heterogeneous expression (right).
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    Image Search Results


    A) Msi2 is expressed in the Lin - EpCAM + lung epithelial cells of Msi2 GFP/+ (M2GFP) reporter mice. Representative FACS plots shown for non-reporter (Msi2 +/+ , left) and M2GFP reporter mouse lungs (Msi2 eGFP/+ middle). Frequency of M2GFP-expressing cells in lung epithelia (right; n = 2 non-reporter, n = 5 reporter). Data represented as mean ± SD, one outlier identified and removed using the Grubb’s test, ***p < 0.001 by Student’s t-test. B-C) Msi2 is expressed in the known stem cell populations of the distal lung. B) Frequency of Msi2 expression in the Lin - EpCAM + Sca1 + enriched Club/BASC and the Lin - EpCAM + Sca1 - enriched AT2 cell populations (n=5). C) Representative images of cytospins from M2GFP reporter mouse Lin - EpCAM + lung epithelial cells showing expression of Msi2 expression in Club cells (top row, marked by CC10 staining) and AT2 cells (bottom row, marked by SPC staining). D) Representative images of Msi2 in tumors from KP f/f mice; some tumors display ubiquitous expression of Msi2 (left), while others display more heterogeneous expression (right).

    Journal: bioRxiv

    Article Title: Regulation of lung cancer initiation and progression by the stem cell determinant Musashi

    doi: 10.1101/2024.04.11.589053

    Figure Lengend Snippet: A) Msi2 is expressed in the Lin - EpCAM + lung epithelial cells of Msi2 GFP/+ (M2GFP) reporter mice. Representative FACS plots shown for non-reporter (Msi2 +/+ , left) and M2GFP reporter mouse lungs (Msi2 eGFP/+ middle). Frequency of M2GFP-expressing cells in lung epithelia (right; n = 2 non-reporter, n = 5 reporter). Data represented as mean ± SD, one outlier identified and removed using the Grubb’s test, ***p < 0.001 by Student’s t-test. B-C) Msi2 is expressed in the known stem cell populations of the distal lung. B) Frequency of Msi2 expression in the Lin - EpCAM + Sca1 + enriched Club/BASC and the Lin - EpCAM + Sca1 - enriched AT2 cell populations (n=5). C) Representative images of cytospins from M2GFP reporter mouse Lin - EpCAM + lung epithelial cells showing expression of Msi2 expression in Club cells (top row, marked by CC10 staining) and AT2 cells (bottom row, marked by SPC staining). D) Representative images of Msi2 in tumors from KP f/f mice; some tumors display ubiquitous expression of Msi2 (left), while others display more heterogeneous expression (right).

    Article Snippet: H&E-stained slides were scanned using Aperio AT2 digital whole slide scanning (Leica Biosystems), and tumor analysis was performed using ImageScope (Aperio).

    Techniques: Expressing, Staining